Some Interesting Facts About Telomeres
In modern times, you see a lot of use for telomerase analysis technology (TAT) in the field of medicine. In a nutshell, this test is a biomarker that is capable of determining risks and early prognosis o of certain illnesses like cancer. The process involves a comprehensive analysis and evaluation of the length of the telomere. Telomere length has been noted to be an essential factor in age-related diseases. Telomeres can be used as either an independent biomarker or in combination with other biomarkers. Telomeres are very convenient biomarkers because you can get them from various body samples. To understand more about telomerase analysis technology, it helps if you get to know telomeres first and foremost. For some noteworthy facts about telomeres, find out here and get info.
As previously stated, there is a link between the length of your telomeres and age-related health conditions. Aging is a normal life occurrence. Until this time, there are many questions about aging like its causes and why a person ages that even scientists are truly baffled. Many theories are published year after year, such DNA being affected and damaged by oxidative stress. Should glucose be blamed as well? What about the cells of the body just all along following a biological timetable that is pre-programmed? While there are many theories, one thing is for sure: there are many causes of aging.
If you look at one theory that resonates a lot, it would have to be that telomeres are associated with the aging process. Your chromosomes are essentially composed of DNA molecules whose ends come with protective caps that you call telomeres. Their primary role is to prevent the ends of your chromosomes from sticking with each other or fraying.
When cells go through division, telomeres make sure that the person’s DNA will be copied properly. However, there are times during DNA replication that the building blocks or nucleotides at the strand’s end are not included in the new copy of the DNA. This leads to the loss of some important genetic information. DNA strands naturally shorter with every division of the cells.
So, how come cells still have some DNA left after the division they’ve undergone? This part is where telomeres play a significant role. Telomeres comprise the same DNA sequence repeated time and time again, making them somehow disposable. They serve the purpose of keeping the rest of your DNA protected. Even if they get shorter time and time again, they will make sure not to lose your genetic information.
When telomeres shorten, some scientists believe that it is one of the factors that cause aging of the cells. Cells cannot divide like they should when they have too short telomeres. Once these cells reach a crucial point, the cell will no longer be active making it either die or slowly accumulate some damage that it cannot fix.